SMART Core

Sequencing, Molecular Analysis & Research Technology

Genomics & Bioinformatics

The SMART Core provides centralized genomic, bioinformatic and biostatistical services to investigators at universities and colleges throughout West Virginia. Supported by NIH grants including WV-INBRE, we offer a comprehensive "full-service" model from experimental design through data analysis.

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Core Services

Next Generation Sequencing

  • Whole genome sequencing (WGS)
  • Whole exome sequencing (WES)
  • RNA-Seq (bulk and single-cell)
  • Microbiome studies
  • Global chromatin & methylation studies

Bioinformatics & Biostatistics

  • Experimental design consultation
  • Data analysis for NGS projects
  • Statistical support
  • Results interpretation
  • Access to sequence analysis software

Conventional Genomics

  • Automated Sanger DNA sequencing
  • Genotyping services
  • RNA/DNA quality assessment
  • Shared instrumentation access
  • Technical consultation

Shared Instrumentation

  • Plate readers
  • Real-time thermal cyclers
  • Agilent Bioanalyzers
  • Fluorimeters
  • Spectrophotometers

Full-Service Workflow

1

Initial Consultation

1-2 meetings

Meet with Genomics/Bioinformatics Core staff to formulate experimental design

2

Project Planning

Within 1 week

Receive expected outcomes, cost quote, and estimated time to completion

3

Service Execution

Varies by project

Core performs sequencing, analysis, or provides instrument access

4

Data Review

1-2 meetings

Core staff meets with investigator to review data and address concerns

Note: WV-INBRE program investigators are required to follow the full-service model. Investigators with independent funding are encouraged to conference with core staff but may formulate their own experimental design.

Service Requirements

Funding Source

WV-INBRE program investigators or investigator-initiated funding

Platform Access

All service requests through Agilent CrossLab (iLab Core Operations)

Registration

Required registration in CrossLab before service requests

Acknowledgment

Required citation of core and grants in publications

Publication Requirements

  • Please acknowledge the Genomics Core Facility
  • Please acknowledge the Bioinformatics Core Facility
  • Cite the WV-INBRE grant: P20GM103434
  • Cite the COBRE ACCORD grant: 1P20GM121299
  • Cite the WV-CTSI grant: 2U54GM104942

Frequently Asked Questions

Contact & Access

Genomics Core Team

Genomics Core Team

Marshall University

genomics@marshall.edu
(304) 696-XXXX

Grant Support

WV-INBRE (P20GM103434)
COBRE ACCORD (1P20GM121299)
WV-CTSI (2U54GM104942)

Supported by the National Institutes of Health (NIH) through these grants. Acknowledgment in publications is required.

Service Timeline

Initial Consultation
1-2 weeks
Project Planning
1 week
Service Execution
Project dependent
Data Review
1-2 weeks